46歳の女性にみられた腎摘後14年目に孤立性脳転移をきたした腎細胞癌の1例を報告する.患者は突然, 頭痛, 失語, 歩行障害, 右片麻輝をきした.脳CTでは左側頭部に嚢胞性腫瘍を認め, これは外科的に完全に切除された, 脳腫瘍の顕微鏡的所見は, 腎細胞癌の原発巣と類似していた, 脳腫瘍は免疫組織学的にEMAとケラチン陽性で, 転移性腎細胞癌の診断が確認された.本症例は腎摘後10年以上へて孤立性脳転移をきたした第2例目の症例である,We report a case of solitary brain metastasis from renal cell carcinoma (RCC) 14 years after nephrectomy. A 46-year-old female had sudden onset of headaches, aphasia, gait disturbance and right hemiparesis. A brain CT revealed a cystic tumor in the left parietal area, which was surgically removed completely. Microscopic appearances of the brain tumor were similar to those of the primary RCC. Positive immunoreaction for epithelial membrane antigen (EMA) and keratin confirmed the diagnosis of metastatic RCC. This is the second case of solitary brain metastasis from RCC occurring more than 10 years after nephrectomy
