1)男子尿道炎160例において, Taylor-Robinson液体培地およびアルギニン加PPLO液体培地を用いてU. urealyticumとM. hominisの検索を行った.淋菌性尿道炎での分離頻度はともに7.1%, 非淋菌性尿道炎ではそれぞれ15.8%, 6.3%であった.2)非淋菌性非クラミジア性で起炎菌不明の尿道炎のうち, U. urealyticumまたはM. hominisが103 ccu/ml以上検出されたのは, それぞれ2例および1例であり, これらマイコプラズマを起炎菌とする男子尿道炎は少数であったWe conducted a multi-center clinical study to evaluate the role of Ureaplasma urealyticum and Mycoplasma hominis in male urethritis. The incidence of each organism in first-voided urine samples of 160 male urethritis patients, including 28 with gonococcal and 126 with non-gonococcal urethritis, was investigated. U. urealyticum and M. hominis were isolated from 13.6% and 6.5%, respectively, of the urine samples, and the concentration of each mycoplasma exceeded 10(3) ccu/ml (color changing units/ml) in 5.2% and 3.9%, respectively. Among 64 patients with non-gonococcal non-chlamydial urethritis, U. urealyticum and M. hominis concentration exceeding more than 10(3) ccu/ml were detected in only two and one samples, respectively. The incidence among urethritis patients with a concentration of either mycoplasma exceeding 10(3) ccu/ml was not significantly greater than that among subfertile males without urethritis. The findings of the present study suggest that, although mycoplasmas may cause urethritis in some patients, the incidence of urethritis due to U. urealyticum or M. hominis is low among patients with non-gonococcal, non-chlamydial urethritis