We present results of a study of neutrino oscillation based on a 766 ton/year exposure of KamLAND to reactor antineutrinos. We observe 258 v_e candidate events with energies above 3.4 MeV compared to 365.2±23.7 events expected in the absence of neutrino oscillation. Accounting for 17.8±7.3 expected background events, the statistical significance for reactor v_e over bar (e) disappearance is 99.998%. The observed energy spectrum disagrees with the expected spectral shape in the absence of neutrino oscillation at 99.6% significance and prefers the distortion expected from v_e oscillation effects. A two-neutrino oscillation analysis of the KamLAND data gives Δm^2=7.9_(-0.5)^(+0.6)x10^(-5) eV^2. A global analysis of data from KamLAND and solar-neutrino experiments yields
Δm^2=7.9_(-0.5)^(+0.6)x10^(-5) eV^2 and tan^2θ=0.40_(-0.07)^(+0.10), the most precise determination to date
