Galactic cosmic ray (GCR) measurements of the phosphorus, sulfur, argon, and calcium isotopes made by the Cosmic Ray Isotope Spectrometer aboard the Advanced Composition Explorer are reported over the energy range from ~100 to ~400 MeV nucleon^(–1). The propagation of cosmic rays through the Galaxy and heliosphere is modeled with constraints imposed by measurements. Isotopic source abundance ratios ^(31)P/^(32)S, ^(34)S/^(32)S, ^(38)Ar/^(36)Ar, and ^(44)Ca/^(40)Ca are deduced. The derived ^(31)P/^(32)S ratio is 2.34 ± 0.34 times larger than the solar system value, lending further credence to the suggestion that refractory elements are enriched in the GCRs due to the sputtering of ions off grains in the cores of superbubbles. By determining the GCR source abundances of argon (a noble gas) and calcium (a refractory), it is determined that material in grains is accelerated to GCR energies a factor of 6.4 ± 0.3 more efficiently than gas-phase material in this charge range. With this information, the dust fraction of phosphorus and sulfur in the interstellar material that is mixed with stellar ejecta to form the GCR seed material is found to be consistent with astronomical observations
