Regiocontrol by Remote Substituents. A Direct Total Synthesis of Racemic Hongconin

Abstract

The total synthesis of hongconin (1) has been completed. Key steps include the metalation of a benzylic alcohol, the formation of a six-membered ring ether via a mercury-mediated cyclization, and the regioselective installation of the naphthalene ring by way of a Diels-Alder reaction

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