Waterhemp continues to be one of the most problematic weeds for Iowa farmers. A higher frequency of waterhemp escapes was observed in Roundup Ready soybean fields during 2001 than in previous years. Control failures may be caused by unfavorable weather, tolerant/resistant biotypes, improper application timing, poor spray coverage, and late emergence. Sorting through these variables can be difficult, but is important in adjusting management programs to avoid repeat problems