Soybean cyst nematode (SCN) was first found in Iowa 30 years ago and it has quickly spread throughout the state and is a major threat to soybeans. SCN management involves growing non-host crops and SCN-resistant soybean varieties. There are hundreds of SCN-resistant varieties available, but almost all have PI 88788 as the source of resistance. Some SCN-resistant varieties have not performed well in certain fields, and SCN populations that can reproduce on PI 88788 may be developing due to frequent use of varieties with resistance from PI 88788. This research effort was designed to identify SCN-resistant varieties that will perform well in these problem areas and help manage SCN populations for long-term soybean profitability