Dipyrromethane based receptors for anions

Abstract

This thesis is principally concerned with the synthesis of a range of dipyrromethane based receptors and their ability to bind anions, in particular carboxylates of amino acid derivatives.Chapter I provides a general introduction to the field of Supramolecular Chemistry and its applications. In this chapter a series of receptors for anions are presented their properties discussed. A particular attention is given to the aromatic heterocycles based receptors and to enantioselective receptors.Chapter II describes the synthesis of a series of acyclic receptors which are the results of subsequent modifications of a simple tweezer, based on a dipyrromethane unit coupled with two butyl amines, previously studied by the group.1 The binding properties with a series of anions are presented and, for the chiral receptors, the binding properties with Nprotected amino acids were investigated.Chapter III describes the synthesis and the binding properties of a series of macrocycles obtained by modifications of the tweezer receptors. The binding properties of the macrocyclic receptors with a series of anions and amino acids are also presented