Advances in neuroscience research have shown that depression and anxiety are closely related to affect regulation, the emotional processes that work within the brain system. This paper reviews two major areas of affect regulation. The first area accounts for the relationships between affect regulation and the functions of the left/right hemispheric brain, as well as the effect of these emotional processes on the autonomic nervous system. The interpersonalneurobiological basis of affect regulation is also elaborated. The discussion implies that depressed and anxious individuals with seriously disturbed emotional or cognitive processes could probably benefit from the enhancement of right hemispheric brain processes via nonverbal form of communication. With capabilities of strengthening emotional and nonverbal processes that occur in the right hemispheric brain, nonverbal forms of psychotherapy, including art therapy, could have benefits in the treatment of depression and anxiety. On the theoretical basis of affect regulation, the second area of discussion focuses on how the assessment and healing functions of various art media adopted in art therapy treatment correlate with left/right hemispheric brain processes. The discussion sheds light on the therapeutic use of art media to allow individuals with mood problems to experience, express, and communicate emotions effectively via nonverbal forms of treatment. The mind-body approach and the various processes of art therapy treatment can attune psychophysiological processes and help to integrate brain processes holistically to improve affect regulation and enhance well-being.published_or_final_versio
