MiR-141 not only modulates anoikis resistance of ovarian cancer cells but also alters pre-metastatic niche for ovarian cancer cell metastatic colonization
Conference Theme: From Cancer Biology to the ClinicINTRODUCTION: Epithelial ovarian cancer (EOC) is the most lethal gynecologic malignancy worldwide. This disease is generally called the ‘silent killer’ because there are no symptoms and thus, the majority of patients are found in advanced stages accompanied by extensive metastasis. Most deaths from this cancer are attributed to metastatic progression. The cancer metastasis is determined by the priming of metastatic niche and the intrinsic properties of cancer cells to adapt ...postprin