Poster Discussion Session - B30. Beast is Inside: What Causes the Adverse Outcomes of Sleep Disordered Breathing: no. A2704RATIONALE: Obstructive sleep apnea (OSA), characterized by intermittent hypoxia (IH), is highly associated with obesity. Depot-specific adipogenic differentiation, an important physiological mechanism in maintaining adipose tissue homeostasis, could be regulated by intracellular transcriptional factors, extracellular signaling pathways and inflammation in obesity. However, the impact of IH on adipogeneisis is unclear. This study aims at investigating the pathologic role of IH during the adipogenic differentiation process in human subcutaneous preadipocytes in …published_or_final_versio
