Grid infrastructures coupled with semantic web linkage and reasoning open up intriguing new possibilities for scientific collaboration. In this short paper, we outline the research agenda and collaboration technologies under development within the CoAKTinG project: Collaborative Advanced Knowledge Technologies in the Grid. CoAKTinG will provide tools to assist scientific collaboration by integrating intelligent meeting spaces, ontologically annotated media streams from online meetings, decision rationale and group memory capture, meeting facilitation, issue handling, planning and coordination support, constraint satisfaction, and instant messaging/presence. Their integration is illustrated through an extended use scenario