The International Society for Magnetic Resonance in Medicine (ISMRM).
Abstract
A second contrast mechanism SEEP was reported to co-exist with BOLD during fMRI activation. The mechanism was based on the task-induced signal
change of extravascular water protons and was primarily shown in the spinal cord at high field. Recently, a preliminary study was reported at 0.2T showing
SEEP contrast in the brain while the BOLD effect was negligible. The present study is to investigate the presence of SEEP in the spinal cord at 0.2T using
proton density-weighted imaging with motor task. Bilateral activations were obtained in the anterior grey horns consistently across C6-C8 levels, which
correlated with the neural anatomy.published_or_final_versio