Law, SYK

Tong, DKH

Wong, J

Wong, KH

HKU Scholars Hub

TitleStandardized uptake value (SUV) in PET/CT for esophagealcancer correlates with pathological stage and predicts R-category of resectionAuthor(s) Law, S; Wong, K; Tong, DKH; Wong, JCitation15th United European Gastroenterology Week (UEGW 2007),Paris, France, 27-31 October 2007. In Gut, 2007, v. 56 n. Suppl 3,p. A223Issued Date 2007URL http://hdl.handle.net/10722/57416Rights Gut. Copyright © B M J Publishing Group.STANDARDIZED UPTAKE VALUE (SUV) IN PET/CT FOR ESOPHAGEAL CANCER CORRELATES WITH PATHOLOGICAL STAGE AND PREDICTS R-CATEGORY OF RESECTION Number: TUE-G-155 Authors: Law S., Wong K., Tong D.K.H., Wong J. Institutions: Department of Surgery, University of Hong Kong Medical Centre, Hong Kong, China Session: Upper GI – Oesophageal malignant disease INTRODUCTION: PET / CT is increasingly used in the staging of oesophageal cancer. The implication of the value of standardized uptake value (SUV) is not fully known.  AIMS & METHODS: It is hypothesized that SUV has correlations with other clinico-pathological data and that it may have prognostic significance. Forty-five patients who had staging PET/CT performed for squamous cell cancer of the oesophagus were studied. The SUVmax values detected on the primary tumour on the scan were correlated with clinico-pathological data and survival in patients after surgical resection. All patients had surgical resection as the only treatment.  RESULTS: There were 31 men and 14 women with a median age of 67 yrs (range: 22–87). Tumors were located in the upper: middle: lower oesophagus in 5, 25 and 15 patients. SUV had no correlation with age, gender, level of tumour and tumour differentiation. Increasing SUV value correlated with advancing pT-stage (p = 0.005), overall p-stage, (p = 0.01), and R1/2-category of resection (p = 0.03), but not to pN status (p = 0.4). Logistic regression analysis of factors predictive of a R1/2 resection identified SUV and advanced age as the only two significant factors. A cut-off point of 11.6 seemed best to separate patients with different pT stages, p-overall stages, and R-categories of resection. SUV however had no significant correlation with long-term prognosis.  CONCLUSION: SUV in PET/CT for oesophageal cancers correlated with pathological stage of disease and was predictive of R-category of resection, which in turn was the most powerful predictor of survival. Gut 2007; 56 (Suppl III) A223  

Standardized uptake value (SUV) in PET/CT for esophageal cancer correlates with pathological stage and predicts R-category of resection

Standardized uptake value (SUV) in PET / CT for oesophageal cancer correlates with pathological stage and predicts R-category of resection

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Standardized uptake value (SUV) in PET/CT for esophageal cancer correlates with pathological stage and predicts R-category of resection

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