Chiu, GKC

Jin, LJ

Leung, WK

Samaranayake, LP

Journal of Dental Research

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Title Oral microbiological and physiopathological status of postirradiated nasopharyngeal carcinoma patientsOtherContributor(s)The 11th Annual Scientific Meeting of IADR Southeast AsianDivision, Jakarta, Indonesia, 4-5 October 1996. In Journal ofDental Research, 1997, v. 76 n. 5, p. 1219Author(s) Leung, WK; Jin, LJ; Samaranayake, LP; Chiu, GKCCitationThe 11th Annual Scientific Meeting of IADR Southeast AsianDivision, Jakarta, Indonesia, 4-5 October 1996. In Journal ofDental Research, 1997, v. 76 n. 5, p. 1219, abstract no. 81Issued Date 1997URL http://hdl.handle.net/10722/53202Rights Creative Commons: Attribution 3.0 Hong Kong LicenseJ Dent Res 76 (5) 1997 Divisional Abstracts: Sotutheast Asian Division 121979S Distribution of Severe Periodontitis Destructive Condition in Urban and RuralThailand. Y. SONGPAISAN*, N. HONGPRASONG, V. BUATONOSRI, P.PHLANTMVANIT. (Mahidol Univ, Thammasat & Chulongkcom Univ., BangkokThailand).The purpose of this report was to compare the periodontal status of nura and urban Thaipopulation.The cross-sectional study for severe periodonmtl destructivc condition was carried outin 35-55 years old Thai population, botb males and females. All first and second molars andcentral incisors (12 teeth) of the total of 1,167 nral ftamers from 4 villages in Payao provisnceand 654 urban bank employee from Bangkok were examined using CPITN. The percentage ofpersons having at least one tooth with severe periodontal destructive condition, CP'fN scored4, was higber in mrral (27.9%) dtan in urban (17.0%). Significant differences of the mean numberofteeth in various CPfIN scores were found among the 12 teeth examined, i.e. CPITN 4: nral4.3±1 92 vs. uban =33=1.86 (p<.OO) and CPITN 3: talrs 5.4±3.09 v.s. urban - 4.7±2.13(p<0.00l). The most co=mon scored CPlTN4 4-teeth were the right second molars. i.e. #17(54.1Y%) and #47 (52.0%) whereas the lower incisors, i.e. #31 (3.1%) and #41 (8.9%) were theleantaffeted. The study showed that severe p_rodoutitls destrucive condition was hig__rin rural pooulatiu than in urban nopulation. Tlhs weems to be similar to the destructivepenodontal condition between iK the dveloping countries and the industrialised counties wbichbaa been reported. Suppoted by Chulalonokom University Rajadapiasek Sompoj Reseuch Fund.81 Oral microbiological and physiopathological status of post irradiated nasopharyngeal81 carcinoma patients. W.K. LEUN'G*, L.J. JIN, L.P. SAIMlANARAYAKE & G.K.C. CHIU(Periodontology & Public Health and Oral Biology Unit, The University of Hong Koag)Objective. To investigate the oral microbiological and physiopathological status of post-iiatednasopharyngeal carcinoma (NPC) patientis. Study design. 33 NPC patienits (mean age 53±10 yr) whocompleted head and neck irradiation therapy (3.3±3.0 yr post-operation) were screened for oralmucosal lesions. 52% of the subjects had not received pos1-irradiation dental care. Stimulated wholesaliva (SWS) flow rate, pH, buffer capacity, carriage rate of cariogenic mnicro-organisms,enterobacterta and yeasts were assessed. Results. All subjects had xerostomia (SWS flow rate:0.04±0.04 ml/min) and 58% had candidiasis. Both SWS pH (6.4±0.6) and buffcring capacity were lowwhilc Streptococcus mutant and Lactobactllus spp. carriage were extremely high (1.4xl07+2.Oxlt07and 2.4xt06±5.7xl106, respectively). 70% of the subjects were found to be harbouring at least onespecies of enterobacteria including Acinetobacter spp., 15%; Chryseomonas luteola, 12%; Citrobacterfrvundli, 6%A; Enrerobocter cloacae, 18%; Escherichia coli, 3%; Flavimonas ory2ihablans, 3%; andPseudomonas aeruglnosa, 12%/. All subjects were carrying at least one specics of yeast, namolyCandida albtcanu, 73%; C. tropfcalis, 27%; C. famata, 3%; and C parasilosis, 3%. Conclusion. 33mHong Kong NPC painsconstituted a high risk group for detal carieL, and oral fungal infection,Thrisk of developing such disease appea t h v high re sin parsdue to insufficient mstMirrad -Iazntal.ar This project was supported by CRCG ofHong Kong.Histologic Finding of Embryonic Tooth Germ Caused by Fluo83 ride NaF. RADIOSUNU (Dept. of Pedodontics. Facultyof Desatistry, Gadjah Mada University, Yogymkarta,INDONRSIA).The aim of this study was to examine the role of fluoride in Nal tothe growth and development of embryonic rat's tooth germ. PregnantAlbino Vester rats at age 3 montls divided in to 2 groups : CONTROLgroup (administrated by isotonic solution); Nl?m group (administratedby 0.02 igras Na! in 0.02 ml destilated water). Intraperitonal injec-tion was given by 1 cc, once in 2 days. On day 15 and 18, pregnantrats were killed and their embryonic tooth germ were subjected toLIGHT MICROSCOPIC. The fluoride content was analized by SPADN'S REAC-TION spectrophotometric method, using a UV-VIS speotrophotometerinstrument. Histologic finding analyzed by LIGHT MICROSCOPE. Theresult of the study were as follows : fluoride content in embryonictooth germ on day 15 and 18 control group < NaP group (p<O.O). Thisdifference was significant (p<O.O1) am tested by IBOVA. The result ofhistologic finding of eabryonic tooth germ on day 15, was at the timeon BELL STAGE, it is the time of enamel organ proliferation in oralepithelium. On day 18, the morphologic of tooth germ on bell stage hasadvanced and was at the time of COMPLETE BELL STAGE. LL la conelnded.thaL an, diffzane histolonic finding cnnntri and kin! siM=a cLombrynni innLh gazao daz mas 1a_. althouah theremAysa aignificndiffnrznoe an flunoidA contentL This study was supported by Gadjahhada University, Ministry of Education and Culture. Indonesia Gover-ment.De/ rcmineralization from different commercial dentiftices: a pH-cycling study85 A ITTHAGARUN*, S.H.Y. WEI, and J.S. WEFEL6. (Department ofChildren's Dentistry and Orthodontics, The University ofHong Kong, HongKong; 6Dows Institute for Dental Research, The University of Iowa, USA).In our previous study, F uptake of dentifrices manufactured locally in some developingcountries have been evaluated and compared (JDR, 1996;75 :194). The objective of this studywas to compare the det reinneralization effects of those dentifrices such as Maxam TartarControl*, Advanced Formula Crest",Colgate MFP2 and one non-fluoride dentifrice ascontrol, by using a single section technique (Wefel et al., JDR, 1987,66 1485-1489) with thepH cycling model (Heilimiart et al.,JDR;1991;70:493). Sound molars were painted, leaving the1 inm wide 'window' on the buccal and/or lingual side, placed in the demineralizationsolution for 96 h to produce artificial caries, 100-120 pm deep. The teeth were thenlongitudinally sectioned, 100pm thick, and randomly dividod into 4 groups (4sections/group). The pit cycling model was utilized for 10 days. Polarized light nsicroscopyand rmicroradiography were used to evaluate the lesiondeptls, lesion area and mnineral contentof the lesion before and after treatment. The control group showed an increase in lesion depthof 51%, and was statistically different from all test groups which ranged fromn -7% to 18%(p0.05 to p<0.01, ANOVA and t-test). No statistical difference was observed among thefluoride containing gioups The it) vitro single section technique used witli pH cycling in thisstudy was able to successfully show lesion progrension and mineral changes in the initiallgsiosg.. (Supported its part by CRCGrant: 345/251/0058, The University ofHong Kong)nRelaion beween Severe Periodontiis and Smoking Habits. P PHANTUMvANIT*,80 N. HONGPRASONO, V. BIATONGSPL, Y. SONOPAISAN & N. CLARKE.(Thamma & Chulalongkom Ufniv, Mahidol Univ, Bangkok Thailand; Univ ofAdelaide, Adelaide. Austlia)The prpose of this study was to examine the relationship between smoking and theoccutrence of severe periodontal breakdown in ral and urban Thai popution. Theretrospective epidemioldgical study was canied in 200 nural (Payao) and 111 urban(Banigkok) severe penodontitis (CP[TNW4) subjects, both maes and females. A set ofquestionnaires relating to smoldng habits and number of cigaret smoking per day wascompleted by subjects. The findig showed that there were siore smokers in rural (50.8%)than urban (30.4%7) subjects (p<O.OO). But most of the urban subjects smoked 10-20cigaretteday(75.0%/o) wher most ofthe nurl subjects smcked less than 10 cigarette/day(84.9w/6). There was no significance difference between the percentage ofCPITN 4-personin smoking and non-smoking subjects in both the urban (27.8 v.s. 28.5) and rural (34.8 v.s.36.5) groups. However, the prevalence of severe pcriodonfitis was significantly differentbetween urban and nual subjects (pcO.0l). The ata indicates that sever eriodoatitismay not relate oly to smoki_g habitsigt ofker rik facr that s_guldJosnsidereconcurrentlv. Suppotted by Chulaogorn University R4jadaisek Sompoj Research Fund.82 Comparative Study of Diabetic and Non-diabetic Saliva.E. Benjavongkulchai*, C. Srewong and S. Ruksasin (ChulalongkornUniv., BKK, Thailand).Glucose and other components of saliva from diabetic and non-diabeticpatients have been previously determined and compared. Yet, no conclusiveresults have been made. In this work, we analysed pH, flow rate, glucose andtotal protein concentrations in diabetic and non-diabetic saliva and also studiedthe corresponding amylase activity and protein pattern under SDS-PAGE. Thestimulated whole saliva samples were collected from twenty non-diabetics andforty non-insulin dependent diabetics between 7.00-8.00 am. The resultsindicated no significant difference between the two tvDes of saliva exceDt forthat glucose concentration of diabetics was significantly hiaher than non-diabetics. This work was supported by Dental Research Fund, Fac. ofDentistry, Chulalongkorn Univ.84 An increment of acid resistance on pit and fissure in human dental enamel bylsr irradiation.A. BAHAR. (Dept. ofPreventive and Public Health Dentistry, Faculty ofDentistry, UJniversity of lndonesia, Jakarta, Indonesia).The acid resistance of pit and fissure enamel in human dental enamel byusing normal pulsed Nd-YAG laser was examined. Morover, the pit andfissure of dental enamel were topically applied with a solution of acidulatedphosphate fluoride (APF) after laser irradiation. The acid resistance ofthe pitand fissure enamel was evaluated by the amount of dissolved calcium persquare millimeter of the surface area. The amount of dissolved calcium inacid solution was determined with an atomic absorption spectrophotometer.The areas of pit and fissure exposed to the laser and acid solution werecalculated by a three dimensonal computed image analyzer. The laserirradiation caused about 40% acid resistance to the pit and fissure enamel.The combination of laser irradiation and APF aDplicatign revealed treateracid recistance. tn the nit and fumi.rn thshn ls,e.r irroMaLwLm ;A no4Antunicotic Effect of Sereh to Candida albicans' Growtfi on iientur86 E. WAUYUNINOTYAS (Gadjah Mada University, Yogyakarta,Indonesia ).This research determinod the antimicotic effect of Stroh to Candida albicauis' growthand the transverse strength of denture. Denture snmear from intlamnmatod mucous wascultivated on Sabaroud's medium. Diffusion and well's methods wer usod forsensitivity test. Sixty samples were divided islto 4 groups concentration. The radicalzone on each well was observed by sliding caliper. The sixly specimens of transversestrength were divided into 3 groups concentration ( 5%, 10% and 15% ). Each groupwas dividod into 2 soaking duration ( 10 minutes and 10 hours). The transverse strengthtest was done by Universal Testing Machine. There was significant difference amongCandida alblcans' growth in different coniceitrations (p<O.001). 'here was significantdifference in tansverse strength between concentrations and soaking duration(p<0.00l) as tested by ANOVA. Screh had antimicotic offoct to Candidaalhic'srowth and it afficted the transverse strength ofacrylic resin in clinzical tolereMce.i-.- 1%1%. I&P-allu I la3ulv ulmi jabur in-duiation aione,

Oral microbiological and physiopathological status of post irradiated nasopharyngeal carcinoma patients

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Oral microbiological and physiopathological status of post irradiated nasopharyngeal carcinoma patients

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