アミノ酸変異及びX線結晶解析を用いたリゾチームの安定性と変性の遷移状態の解析

Abstract

GERERAL INTRODUCTION CHAPTER I Correlation Between the Differences in the Free Energy Change and Conformational Energy in the Folded State of Hen Lysozymes with Gly-Pro and Pro-Gly Sequences Introduced to the Same Site CHAPTER II Analysis of the Transition State in the Unfolding of Hen Lysozyme by Introduction of Gly-Pro and Pro-Gly Sequences at the Same Site CHAPTER III Analysis of the Stabilization of Hen Lysozyme with the Helix Microdipole and charged Side Chains CHAPTER IV Influence of Mutations of not Conserved N-Cap Residue,Gly4,on Stability and Structure of Hen Lysozyme CONCLUSIONMade available in DSpace on 2012-09-06T02:51:16Z (GMT). No. of bitstreams: 1 motoshima.pdf: 14085243 bytes, checksum: e6ca814a9b4ebee5d7a95ba8943830ff (MD5) Previous issue date: 1996-03-2