Objective: To analyze the effects of Pilates mat exercises in patients with cystic fibrosis (CF). Methods: This was a clinical trial involving 19 CF patients recruited from either the CF Outpatient Clinic of the State University at Campinas Hospital de Clinicas or the Children's Institute of the University of So Paulo School of Medicine Hospital das Clinicas. All of the patients performed Pilates mat exercises for four months (one 60-min session per week). the variables studied (before and after the intervention) were respiratory muscle strength, MIP, MEP, FVC, and FEV1. Results: After the intervention, MIP was significantly higher in the male patients (p = 0.017), as were MIP and MEP in the female patients (p = 0.005 and p = 0.007, respectively). There were no significant differences between the pre- and post-intervention values of FVC or FEV1, neither in the sample as a whole nor among the patients of either gender. Conclusions: Our results show that Pilates mat exercises have beneficial effects on respiratory muscle strength in CF patients.Univ Estadual Campinas, Campinas, SP, BrazilUniv Estadual Campinas, Programa Posgrad Saude Crianca & Adolescente, Campinas, SP, BrazilUniv Estadual Campinas, Dept Pediat, Fac Ciencias Med, Campinas, SP, BrazilUniv São Paulo, Fac Med, Inst Crianca, Unidade Pneumol Pediat, São Paulo, BrazilUniversidade Federal de São Paulo, Programa Posgrad Reabilitacao, São Paulo, BrazilUniversidade Federal de São Paulo, Programa Posgrad Reabilitacao, São Paulo, BrazilWeb of Scienc
