Objectives: We aimed to evaluate Latin American primary care physicians' knowledge and attitudes about obstructive sleep apnea (OSA) using a Spanish-language version of the OSA Knowledge and Attitudes (OSAKA) questionnaire and to evaluate its psychometric properties.Methods: We used a cross-sectional survey of general practice physicians in Ecuador, Peru, and Venezuela who completed the Spanish-language version OSAKA questionnaire.Results: of 684 primary care physicians surveyed, 367 (65%) responded (mean age, 45 years; range, 21-75 years). Mean total knowledge (proportion of 18 items correctly answered) was 60% (range, 0-100%). Less than half of physicians correctly answered the questions about the association between OSA and hypertension. We found no significant differences in overall knowledge in gender or time since graduation (5 years). Although 73.5% of the physicians felt confident in identifying patients at risk for OSA, only 35.4% felt confident in managing those patients and 22.1% felt confident in managing patients with continuous positive airway pressure (CPAP) therapy. the Spanish-language version of the OSAKA questionnaire had comparable psychometric properties to the English-language version.Conclusions: This Spanish-language version of the OSAKA yielded considerable variance in Spanish-speaking physicians' knowledge about OSA and confidence in identifying and managing patients with OSA. Focused OSA education for Latin American general physicians is needed. (C) 2013 Elsevier B. V. All rights reserved.Kennedy Hosp, Respiralab Res Ctr, Guayaquil, EcuadorWashington Univ, Sch Med, Dept Med,Div Hlth Behav Res, Barnes Jewish Hosp,Alvin J Siteman Canc Ctr, St Louis, MO 63110 USAWashington Univ, Sch Med, St Louis, MO USABrown Univ, Mental Hlth Res Inst, Providence, RI 02912 USACapital Hlth Reg Med Ctr, Trenton, NJ USAUniversidade Federal de São Paulo, Div Resp, São Paulo, BrazilBrown Univ, Dept Med, Alpert Med Sch, Providence, RI 02912 USAMed Ctr La Trinidad, Caracas, VenezuelaClin San Borja, Dept Allergy & Immunol, Lima, PeruHeidelberg Univ, Sch Med, Heidelberg, GermanyUniversidade Federal de São Paulo, Div Resp, São Paulo, BrazilWeb of Scienc