7 páginas, 7 figuras, 3 tablas.-- El pdf del artículo es la versión pre-print.A fast and easy one-step linker-free approach for the synthesis of palladium nanoparticle/multiwall carbon nanotube (Pd-NP/MWCNT)hybrid materials is described using microwave irradiation for the  effective decomposition of Pd2dba3 complex in the presence of MWCNTs. High loadings of Pd nanoparticles (up to 40 wt.%) having sizes  between 3 and 5 nm are deposited on the surface of MWCNTs within a time of only 2 minutess. The Pd-NP/MWCNT materials serve as efficient catalysts in C-C coupling as well as in hydrogenation reactions, all characterized by high conversion rates using a small amount of catalysts, high turnover frequency values and good recyclbility.Financial support from the Spanish Ministerio de Ciencia e

Innovación (MICINN) and the European Regional Development

Fund (ERDF) under projects CTQ2008-01784 and

MAT2007-66927-C02-01, and the Gobierno de Aragón (DGAPI086-

08) is gratefully acknowledged. M.C. thanks MICINN

for her Grant No. BES-2008-003503.Peer reviewe

Behrendt, F.F.

Goedicke, A.

Kuhl, C.K.

Mottaghy, F.M.

Palmowski, K.

Pietsch, H.

Rebiere, M.

Verburg, F.A.

Behrendt, Florian F.

Rebière, Marilou

Goedicke, Andreas Georg

Pietsch, Hubertus

Palmowski, Karin

Kuhl, Christiane

Mottaghy, Felix

Verburg, Frederik Anton

Publikationsserver der RWTH Aachen University

Contrast medium injection protocol adjusted for body surface area in combined PET/CT

OBJECTIVES: To evaluate the effect of contrast medium dose adjustment for body surface area (BSA) compared with a fixed-dose protocol in combined positron emission tomography (PET) and computed tomography (CT) (PET/CT). METHODS: One hundred and twenty patients were prospectively included for (18)F-2-deoxy-fluor-glucose ((18)F-FDG)-PET/CT consisting of a non-enhanced and a venous contrast-enhanced CT, both used for PET attenuation correction. The first 60 consecutive patients received a fixed 148-ml contrast medium dose. The second 60 patients received a dose that was based on their calculated BSA. Mean and maximum standardised FDG uptake (SUVmean and SUVmax) and contrast enhancement (HU) were measured at multiple anatomical sites and PET reconstructions were evaluated visually for image quality. RESULTS: A decrease in the variance of contrast enhancement in the BSA group compared with the fixed-dose group was seen at all anatomical sites. Comparison of tracer uptake SUVmean and SUVmax between the fixed and the BSA group revealed no significant differences at all anatomical sites (all P > 0.05). Comparison of the overall image quality scores between the fixed and the BSA group showed no significant difference (P = 0.753). CONCLUSIONS: BSA adjustment results in increased interpatient homogeneity of contrast enhancement without affecting PET values. In combined PET/CT, a BSA adjusted contrast medium protocol should be used preferably. KEY POINTS : * Intravenous contrast medium is essential for many applications of PET/CT * Body surface area adjustment of contrast medium helps standardise contrast enhancement * Underdosing or overdosing of contrast medium will be reduced * PET image quality is not influenced * BSA adjusted contrast medium protocol should be used preferably in combined PET/CT

NARCIS 

OBJECTIVES: To evaluate the effect of contrast medium dose adjustment for body surface area (BSA) compared with a fixed-dose protocol in combined positron emission tomography (PET) and computed tomography (CT) (PET/CT). METHODS: One hundred and twenty patients were prospectively included for (18)F-2-deoxy-fluor-glucose ((18)F-FDG)-PET/CT consisting of a non-enhanced and a venous contrast-enhanced CT, both used for PET attenuation correction. The first 60 consecutive patients received a fixed 148-ml contrast medium dose. The second 60 patients received a dose that was based on their calculated BSA. Mean and maximum standardised FDG uptake (SUVmean and SUVmax) and contrast enhancement (HU) were measured at multiple anatomical sites and PET reconstructions were evaluated visually for image quality. RESULTS: A decrease in the variance of contrast enhancement in the BSA group compared with the fixed-dose group was seen at all anatomical sites. Comparison of tracer uptake SUVmean and SUVmax between the fixed and the BSA group revealed no significant differences at all anatomical sites (all P &gt; 0.05). Comparison of the overall image quality scores between the fixed and the BSA group showed no significant difference (P = 0.753). CONCLUSIONS: BSA adjustment results in increased interpatient homogeneity of contrast enhancement without affecting PET values. In combined PET/CT, a BSA adjusted contrast medium protocol should be used preferably. KEY POINTS : * Intravenous contrast medium is essential for many applications of PET/CT * Body surface area adjustment of contrast medium helps standardise contrast enhancement * Underdosing or overdosing of contrast medium will be reduced * PET image quality is not influenced * BSA adjusted contrast medium protocol should be used preferably in combined PET/CT

Maastricht University Research Portal

7 páginas, 7 figuras, 3 tablas.-- El pdf del artículo es la versión pre-print.A fast and easy one-step linker-free approach for the synthesis of palladium nanoparticle/multiwall carbon nanotube (Pd-NP/MWCNT)hybrid materials is described using microwave irradiation for the  effective decomposition of Pd2dba3 complex in the presence of MWCNTs. High loadings of Pd nanoparticles (up to 40 wt.%) having sizes  between 3 and 5 nm are deposited on the surface of MWCNTs within a time of only 2 minutess. The Pd-NP/MWCNT materials serve as efficient catalysts in C-C coupling as well as in hydrogenation reactions, all characterized by high conversion rates using a small amount of catalysts, high turnover frequency values and good recyclbility.Financial support from the Spanish Ministerio de Ciencia e
Innovación (MICINN) and the European Regional Development
Fund (ERDF) under projects CTQ2008-01784 and
MAT2007-66927-C02-01, and the Gobierno de Aragón (DGAPI086-
08) is gratefully acknowledged. M.C. thanks MICINN
for her Grant No. BES-2008-003503.Peer reviewe

Cano, Manoli

Benito, Ana M.

Maser, Wolfgang K.

Urriolabeitia, Esteban P.

Digital.CSIC

Carbon