Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2001.Includes bibliographical references (p. 161-165).The medical field, and surgeons in particular, are turning to engineers to develop systems that help them learn their craft better. Mannequin-based systems, animal labs and surgery on cadavers each have drawbacks that could be addressed through realistic computer-based surgical simulation systems. To generate a simulation that includes both tactile/haptic and visual feedback, one must know what the material properties of tissue are, so that a finite element or other model can generate the proper predictions for interactions between surgical instruments and tissue. This thesis presents the design, construction, characterization, and use of a mini- mally invasive surgical instrument designed to measure the linear visco-elastic prop- erties of solid organs. The Tissue Material Property Sampling Tool, or TeMPeST 1-D, applies a small amplitude vibration normal to the surface of an organ such as liver or spleen, and records the applied force and displacement. It has a range of motion of up to lmm, and can apply up to 300mN force with a 5mm right circular indenter. The open loop bandwidth of the system is approximately 100Hz, which is greater than the bandwidth of both the human visual and motor control systems. The relationships between indentation force and displacement and material prop- erties such as the elastic modulus of tissue are presented, and models are developed that show the expected response to a standard tissue model. Characterization and calibration tests demonstrate the response of the prototype components. Experi- ments performed on spring and mass elements and on silicone gel samples, which mimic tissue response, show that the TeMPeST 1-D can accurately measure their force-displacement responses.(cont.) The TeMPeST 1-D and its data acquisition system are intended to be portable, to be easily transported to and used in an operating room. The system was used in proof-of-concept experiments performed on live pigs; an example of the measured properties of porcine liver is presented. The TeMPeST 1-D is the first in a series of instruments that will be developed to support the generation of a comprehensive atlas of tissue material properties.by Mark Peter Ottensmeyer.Ph.D
