Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2006.This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.MIT Institute Archives copy: pages 101-163 bound in reverse order.Includes bibliographical references (p. 141-163).Information storage and retrieval systems are communication systems from the present to the future and fall naturally into the framework of information theory. The goal of information storage is to preserve as much signal fidelity under resource constraints as possible. The information storage theorem delineates average fidelity and average resource values that are achievable and those that are not. Moreover, observable properties of optimal information storage systems and the robustness of optimal systems to parameter mismatch may be determined. In this thesis, we study the physical properties of a neural information storage channel and also the fundamental bounds on the storage of sources that have nonsequential semantics. Experimental investigations have revealed that synapses in the mammalian brain possess unexpected properties. Adopting the optimization approach to biology, we cast the brain as an optimal information storage system and propose a theoretical framework that accounts for many of these physical properties. Based on previous experimental and theoretical work, we use volume as a limited resource and utilize the empirical relationship between volume anrid synaptic weight.(cont.) Our scientific hypotheses are based on maximizing information storage capacity per unit cost. We use properties of the capacity-cost function, e-capacity cost approximations, and measure matching to develop optimization principles. We find that capacity-achieving input distributions not only explain existing experimental measurements but also make non-trivial predictions about the physical structure of the brain. Numerous information storage applications have semantics such that the order of source elements is irrelevant, so the source sequence can be treated as a multiset. We formulate fidelity criteria that consider asymptotically large multisets and give conclusive, but trivialized, results in rate distortion theory. For fidelity criteria that consider fixed-size multisets. we give some conclusive results in high-rate quantization theory, low-rate quantization. and rate distortion theory. We also provide bounds on the rate-distortion function for other nonsequential fidelity criteria problems. System resource consumption can be significantly reduced by recognizing the correct invariance properties and semantics of the information storage task at hand.by Lav R. Varshney.S.M
