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Organocatalytic activation of imines and related compounds through hydrogen-bond interactions
Authors
J. Ignacio Delso
Aranzazu Isasi
+4 more
Rosa Matute
Pedro Merino
David Roca-López
Tomás Tejero
Publication date
23 January 2013
Publisher
'Bentham Science Publishers Ltd.'
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Abstract
Activation of imines by hydrogen bonding is a very powerful way of promoting the synthesis of a variety of nitrogencontaining compounds of interest. Such a useful approach typically involves mild reaction conditions, simple experimental operations and metal-free reagents. The present review focuses on the recent development of new organocatalytic methods involving imines and related compounds as substrates in which activation through hydrogen bonding is performed. The different modes of activation are thoroughly illustrated with special emphasis on mechanistic aspects of the reactions and how activation is actually produced. © 2011 Bentham Science Publishers Ltd.Peer Reviewe
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Last time updated on 25/05/2016