Enterobacter cloacaeis normally considered to be an opportunistic human pathogen. Here, we report on the whole-genome sequence of an endophyticE. cloacae, strain ``Ghats1'', isolated from leaves of the medicinal plantCoscinium fenestratumGaertn. Functional analysis of the Ghats1 genome revealed an enrichment for genes involved in the uptake and exchange of nutrients, for chemotaxis and for plant colonization. Unexpectedly though, there were no ORFs belonging to the ``virulence factors and antibiotic resistance''. Moreover, the presence of hydrolytic enzymes and motility functions reveals the characteristics of an endophyte lifestyle of a bacterium that can colonize and adapt to plant environment. These results provide a better understanding of an endophytic lifestyle through plant-microbe interaction, which can be further exploited as a biocontrol agent
