Synthesis, characterization, thermal, anticancer and dna binding properties of co(ii), ni(ii), cu(ii), cd(ii) and zn(ii) complexes with schiff base

Abstract

A series of metal complexes of Co(II), Ni(II), Cu(II), Cd(II) and Zn(II) were synthesized with newly prepared ligand. This ligand was prepared by the condensation of hydrazide with 2-chloro benzaldehyde. The resulting complexes were characterized by elemental analyses, spectroscopic data i.e. IR, UV, mass, molar electric conductibility as well as magnetic measurements. The complexes were square planar and octahedral in nature. Thermal studies of the complexes were also reported. Metal complexes exhibited DNA binding, cleavage and anticancer activities which were significantly better than the ligand