Atomically thin molybdenum disulfide (MoS2) sheets were synthesized and isolated via solventassisted
chemical exfoliation. The charge-dependent electrochemical activities of these MoS2
sheets were studied using positively charged hexamine ruthenium (III) chloride and negatively
charged ferricyanide/ferrocyanide redox probes. Ultrathin MoS2 sheet-based electrodes were
employed for the electrochemical detection of an important neurotransmitter, namely dopamine
(DA), in the presence of ascorbic acid (AA). MoS2 electrodes were identified as being capable of
distinguishing the coexistence of the DA and the AA with an excellent stability. Moreover, the
enzymatic detection of the glucose was studied by immobilizing glucose oxidase on the MoS2.
This study opens enzymatic and non-enzymatic electrochemical biosensing applications of
atomic MoS2 sheets, which will supplement their established electronic application
