The Structure and Solid-state Conformation of (e)-(9r,10r)-9,10-epoxy-17-beta-hydroxy 4a-oxa-a-homo-5,10-8,9-disecoandrost-3-ene-5,8-dione Acetate

Abstract

the molecular structure of the title compound, a 15-membered 9,10-epoxy-3-en-4-ol lactone, which is an important intermediate in the reaction sequence correlating steroid compounds with prostaglandin-like derivatives, was determined by X-ray analysis. The (E) stereochemistry around the double bond and the trans-(9R,10R)-configuration at the oxirane ring are established