A ease of occupational asthma associated with rhinitis and conjunctivitis occurred in a patient,working in a textile factory and exposed to different coloring reagents is reported Symptoms appeared in phases correlated with changes in the use of the coloring reagents. Prick tests,were carried out with the different coloring reagents and,were positive for the yellow color. The test was followed by a clear increase in bronchial hyperreactivity to methacholine. Some individual preventive measures, such as wearing a face mask, led to reduction then disappearence of the symptoms