Blood flow modeling in peripheral arterial bypasses : from theory to clinical practice

Abstract

Peripheral arterial bypass surgery is affected by a significant occlusion rate at mid-term. The bypass patency depends on its hemodynamics and this later is influenced by the bypass distal anastomosis site (distal arterial network) and the bypass conduit type (venous or prosthetic). We have developed and validated a mathematical model that predicts blood flow in a bypass, depending on the patient-specific arterial network and the bypass conduit characteristics. The pressure wave propagation in peripheral diseased arterial networks and the influence of a revascularization procedure have been described. The arterial networks have been defined by their resistance and compliance characteristics. Arterial segments and bypass conduits have been described by their elasticity. The acquisition methods have taken the occlusion sites and the arterial calcifications into consideration.(MED - Sciences médicales) -- UCL, 201