Zeolite micropattern on biological application

Abstract

Zeolite micropattern created from structurally similar hydrophobic Sil-1 and hydrophilic ZSM-5 zeolites, and tested for the immobilization of fluorescein isothiocyanate conjugate bovine serum albumin (BSA-FITC), biotin conjugate bovine serum albumin (Biotin-BSA), Hochest 33342 and rhodamine conjugate α- bungatoxin, were preferentially deposited onto hydrophobic ZSM-5 patterns regardless of the pattern geometry. Being inorganic, the zeolite micropattern does not deteriorate with time and can be readily reused by simply burning away the deposited chemicals and biomolecules. This suggests that compositional micropattern of zeolite could be used to create high resolution array of biomolecules on flat substrate