In this paper we present a methodology to characterize elastic-plastic constitutive law of metallic materials using spherical indentation tests and parametric identification coupled with finite elements model simulation. This procedure was applied to identify aluminium, copper and titanium mechanical properties and the identified models show difference that do not exceed 10% with experimental uniaxial tensile tests results. A sensitivity study according to a 2^k Design of Experience (DoE) was achieved to determine which data that can be extracted from pile-up is the most relevant to use in order to enhance the identification procedure. It appears that the maximum pile-up height seems to be the best suited for this purpose
