The background of research was high incidence of Dengue Fever in Sragen Regency and the area with highest incidence rate of Dengue Blood Fever was Sragen Sub District. Sragen Sub District is endemic area of Dengue Fever case with ever increasing incidence rate. The Health Office of Sragen Regency is a public organization responsible for the high incidence of Dengue Fever in Sragen Regency. The objective of research was to find out the performance of Sragen Regency’s Health Office in coping with Dengue Fever Case in Sragen Sub District, Sragen Regency. The type of research employed in this study was descriptive qualitative research. Techniques of collecting data used were interview, observation, and documentation study. The sampling technique used was purposive sampling one, while, data validation was carried out using source triangulation meaning to compare and to investigate the reliability of information obtained from different source. The data analysis was conducted using an interactive model of analysis. From the result of research, it could be concluded that the performance of Health Office viewed from Inputs, Outputs, and Outcomes has been running quite well although there are some goals that have not been achieved. Inputs was studied from the legislation becoming reference, human resource, fund, fogging and insecticide availability were investigated showing good result. Output was studied from the realization of Dengue Fever case coping activities that had run well. Meanwhile Outcome, it could be seen from the achievement of three objectives of Dengue Fever management: to decrease illness rate, to decrease mortality rate, and to prevent extraordinary incidence, in which only one objective was achieved, to decrease mortality rate. The inhibiting factors affecting the performance were limited number of fogging personnel, inadequate fogging instrument in Health Office and the society’s less awareness of eradicating mosquito nest. Keywords: Performance, Cope, Dengue Feve
