Sestre Milosrdnice University hospital and Institute of Clinical Medical Research
Abstract
This cross-sectional study aimed to evaluate the association between medication adherence and Health-Related Quality of Life (HRQoL) in 120 hypertensive patients. Personal Information Form, SF-36 Quality of Life Scale (SF-36 QoL) and Medication Adherence Self-Efficacy Scale (MASES) were used for data collection. Data were analyzed with SPSS program using percentage, mean value, standard deviation, significance test of difference between two means, analysis of variance, Mann-Whitney U test, Kruskal-Wallis test and χ2-test. MASES and SF-36 QoL scores of the patients were found to be low. Adherence to medication and compliance were found to be low in males, patients using two or more drugs, and those that did not control their blood pressure regularly. In addition, a statistically significant positive relationship was found between adherence to medication/compliance, self-efficacy and quality of life (p<0.001). Regular and continuous adaptation programs addressing patients on antihypertensive therapy will improve the quality of life of these patients.Cilj ove presječne studije bio je procijeniti udruženost pridržavanja farmakoterapije i kvalitete života povezane sa zdravljem (Health-related Quality of Life, HRQoL) kod 120 hipertenzivnih bolesnika. Za prikupljanje podataka rabili su se sljedeći alati: Personal Information Form, SF-36 Quality of Life Scale (SF-36 QoL) i Medication Adherence Self-Efficacy Scale (MASES). Podaci su analizirani pomoću programa SPSS uz primjenu postotka, testa značajnosti razlike između dviju srednjih vrijednosti, analize varijance, Mann-Whitneyjeva U testa, Kruskal-Wallisova testa i χ2-testa. Vrijednosti MASES i SF-36 QoL dobivene kod bolesnika bile su niske. Pridržavanje farmakoterapije bilo je nisko kod muškaraca, a bolesnici koji su uzimali dva lijeka ili više njih nisu redovito kontrolirali krvni tlak. Uz to, utvrđen je statistički značajan pozitivan odnos između pridržavanja farmakoterapije, samostalnog odlučivanja o tome i kvalitete života (p<0,001). Kvalitetu života ovih bolesnika može se poboljšati redovnim i trajnim programima prilagodbe usmjerenim ka bolesnicima koji uzimaju antihipertenzivne lijekove
