Urinary activity of N-acetyl-beta-D-glucosaminidase in workers exposed to the effects of mercury

Abstract

U skupini 100 ispitanika koji rade u pogonu elektrolize određivana je aktivnost urinarne N-acetil-beta-D-glukozaminidaze i koncentracija žive u urinu. Utvrđeno je da je pomenuta enzimska aktivnost oko dva puta veća u usporedbi sa vrijednostima koje su određene u 100 ispitanika iz kontrolne skupine. Ta je razlika bila statistički značajna, ali nije utvrđeno postojanje pozitivne korelacije između aktivnosti urinarne N-acetil-beta-D-glukozarninidaze i urinarne koncentracije žive. Diskutirano je o mogućnosti primjene ovog biokemijsko-toksikološkog testa u profesionalnoj toksikologiji, odnosno medicini rada.Mercury concentration in urine and urinary activity of N-acetyl-beta-D-gfucosaminidase were determined in a group of 100 workers from an electrolysis workshop. The enzyme activities measured were twice as high as those of 100 control subjects. The difference was statistically significant. There was no correlation between urinary activity of N-acetyl-beta-D-glucosaminidase and mercury concentration in urine. The applicability of this biochemical-toxicological test in occupational health practice is discussed

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