Myxoma is a benign tumor composed of primitive connective tissue cells and mesenchymal mucousal stroma. Also
referred to as, a gelationus or colloidal tumor. Although rare, it can be found in the atrium of the heart, and it is the most
common heart tumor. It has also been described in other body sites, one of which is the bone. We report a case of a 57-yearold
female patient, with recurrent headaches located in the area of the right half of the face. Radiological analysis (Multislice
Computed Tomography of the paranasal sinuses and viscerocranium) was performed, and a formation of irregular
contours, destroying the right zygomatic bone, was described, measuring 25x17x20 mm in its widest diameters. Its medial
border was adjacent to the lateral wall of the right maxillary sinus and the cortical bone in this segment was thinned,
but preserved. A probatory excision was performed in general anesthesia, and the histopathological fi nding showed, starlike
tumor cells embedded in mucoid stroma and infi ltrating the bone. After pathohistological confi rmation of myxoma,
the tumor was excised in total, using infraorbital surgical approach to the zygomatic bone. During the follow-up, the
patient was symptom free, without headaches, and there were no signs of local tumor recurrence. Despite of the fact that
myxoma behaves as a benign disease in its nature, it can cause destruction of the tissue in the vicinity of the tumor itself,
and thus major health issues for the patient. A timely proper diagnosis and the right choice of a surgical treatment can
help avoid more extensive surgery procedures, as shown in our case report
