Side-effects of systemic antitumor therapy

Abstract

Sistemska antitumorska terapija (kemoterapija, imunoterapija, hormonalna terapija) oblik je liječenja koji se sastoji od neprekidne upotrebe lijekova što uništavaju ili kontroliraju rast zloćudnih stanica. Može se davati kao jedan lijek ili kao kombinacija lijekova. Mnogi od citostatika koji se koriste mogu prouzrokovati popratne pojave. Te pojave jako se razlikuju kod pojedinih pacijenata. Kemoterapija djeluje na stanice koje se brzo dijele. To mogu biti normalne stanice, kao i stanice tumora. Posljednjih godina liječimo oboljele ciljanom terapijom (engl. targeted therapy) koja selektivno djeluje na stanice raka, a minimalno na normalne stanice, iako ima neke druge vrste nuspojava.Systemic antitumor therapy (chemotherapy, hormon therapy and immunotherapy) is a form of treatment which consists of continuous use of drugs that destroy or control growth of malignant cells. It can be administered as a single drug or combination of drugs. The drugs used in chemotherapy protocols often cause side effects which are very variable depending of individual patient. Systemic antitumor therapy strong effects on cells that divide rapidly and destroy tumor cells as normal cells. In recent years, we treat our patients with targeted therapies which selectively act on cancer cells, and minimally harm normal cells, although they have some other types of side effects