Synthesis and Fluorescence Properties of 2-Methylamino-6-triazolylpurine Deoxyribonucleoside

Abstract

The fluorescent nucleoside isomorphs are tools used for the exploration of structure and interactions of nucleic acids. For instance, they are employed in single-nucleotide polymorphysm assays and for the investigation of interactions between nucleic acids and drugs. Recently, a method for the synthesis of nucleoside analogues possessing fluorescent properties was reported by our group. This approach is used in the present research for the synthesis of a novel compound. Its fluorescent properties have shortly been examined leading to interesting results