Synthesis and Transformations of 2,6-Diazidopurine Deoxynucleoside
- Publication date
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- RTU Press
Abstract
In recent years a number of 1,2,3-triazolylnucleoside derivatives have been synthesised and investigated, leading to the discovery of substances with antiviral and anticancer activity, enzyme inhibitors, adenosine receptor agonists and antagonists. The aim of this research is to achieve 2,6-diazidopurine deoxyribonucleoside using deoxyguanosine or 2,6-diazidopurine as the starting material, and to investigate its reactions with terminal alkynes