Mapping longitudinal studies to risk factors in an ontology for dementia

Abstract

A common activity carried out by healthcare professionals is to test various hypotheses on longitudinal study data in an effort to develop new and more reliable algorithms that might determine the possibility of developing certain illnesses. The In-MINDD project provides input from a number of European dementia experts to identify the most accurate model of inter-related risk factors which can yield a personalised dementia risk quotient and profile. This model is then validated against the large population-based prospective Maastricht Aging Study (MAAS) dataset. As part of this overall goal, the research presented in this paper demonstrates how we can automate the process of mapping modifiable risk factors against large sections of the aging study and thus, use information technology to provide more powerful query interfaces