The brain is the most complex and least understood biological system known to man. New imaging techniques are providing scientists with an entirely new perspec- tive on the study of the functional brain at a neural circuit level, enabling in-depth understanding of both physiological processes and animal models of neurological and psychiatric diseases which currently lack e↵ective treatments. These new tools come at the cost of meeting the challenges associated with the miniaturization of the hard- ware for in vivo recording