Gender differences in jealously have been traced back to both socio-cultural, as well as to evolutionary sources. The evolutionary approach predicts similar gender differences to be found in all cultures. Socio-cultural explanations, however, suggest that the patterns of gender differences may be culture-specific. The current study investigated gender differences in the relations between jealousy and infidelity in Mexico. 537 participants (248 men; 289 women) filled out an inventory of jealousy and infidelity, respectively. The results show first a positive relationship among infidelity, anger, fear, suspicion, frustration and distrust. Second, the data reveal a clear gender difference in that men desired sexual and emotional infidelity relationships more often than women. These findings are discussed regarding the importance of culture