Conditions for obtaining quantitative .ililformation on the double
layer of colloid particles on the basis of electrosurface measurements
have been analyzed. A rigorous theory of electric conductivdty
of diluted suspensions on the basis of induced dilpole
moments of particles has been presented.
The .isoconductance point of a suspension has been shown to
codncide wd.th the isopolarisation state of a particle. A theory of
anisotropy of the electrophoresis of long rod-like particles has been
put forward. The identity of the formules of electrophoresis of a
sphere and of cylindrical particles oriented pevpendicular towards
the field at a small thickness of the double layer has been shown.
A good agreement has been found between the values of induced
dipole moments and, specific surface conductivity in a wide electrolite
concentration range measured by the methods of electric
conductivity of suspensions and anisotropy of electrophoresis. The
theories of induced dipole moment, electric conductivity of suspension
and anisotropy of electrophoresis have been experimentally
examined

C. Ryan (3402638)

Carol O’Shea (3661864)

Catherine Stanton (223943)

Cian Hill (3461294)

Claire Watkins (3661867)

Denise Lynch (3461288)

Eugene Dempsey (809933)

Fulvio Mattivi (161798)

Ian Jeffery (3421385)

Kiera Murphy (214473)

Kieran Touhy (3661873)

Marynka Ulaszewska (3661876)

Paul O’ Toole (3661870)

R. Paul Ross (152753)

Microbiome

English

PubMed

ErratumFollowing publication of this article [1], it has come to our attention that the name of the author Kieran Tuohy’s name was captured incorrectly as “Touhy” and instead should be Kieran Tuohy. The original article has also been corrected.The online version of the original article can be found under doi:10.1186/s40168-016-0213-y

Hill, Cian J

Lynch, Denise B

Murphy, Kiera

Ulaszewska, Marynka

Jeffery, Ian B

O'Shea, Carol A

Watkins, Claire

Dempsey, Eugene

Mattivi, Fulvio

Tuohy, Kieran

Ross, R Paul

Ryan, C. Anthony

O'Toole, Paul W.

STANTON, CATHERINE

T-Stór

Hill et al. Microbiome  (2017) 5:21 DOI 10.1186/s40168-017-0240-3ERRATUM Open AccessErratum to: Evolution of gut microbiotacomposition from birth to 24 weeks in theINFANTMET CohortCian J. Hill1,2, Denise B. Lynch1,2, Kiera Murphy1,2,3, Marynka Ulaszewska5, Ian B. Jeffery1, Carol Anne O’Shea4,Claire Watkins3, Eugene Dempsey4, Fulvio Mattivi5, Kieran Tuohy5, R. Paul Ross1,2, C. Anthony Ryan2,4,Paul W. O’Toole1,2 and Catherine Stanton2,3*ErratumFollowing publication of this article [1], it has come toour attention that the name of the author KieranTuohy’s name was captured incorrectly as “Touhy” andinstead should be Kieran Tuohy. The original article hasalso been corrected.Author details1School of Microbiology, University College Cork, Cork, Ireland. 2APCMicrobiome Institute, University College Cork, Cork, Ireland. 3TeagascMoorepark Food Research Centre, Fermoy, Co., Cork, Ireland. 4Department ofNeonatology, Cork University Maternity Hospital, Cork, Ireland. 5Food Qualityand Nutrition Department, Research and Innovation Centre, FondazioneEdmund Mach, San Michele All′adige, Italy.Received: 31 January 2017 Accepted: 31 January 2017Reference1. Hill JC, Lynch BD, Murphy K, Ulaszewska M, Jeffery BI, O’Shea CA, Watkins C,Dempsey E, Mattivi F, Tuohy K, Ross PR, Ryan CA, O’ Toole WP, Stanton C.Evolution of gut microbiota composition from birth to 24 weeks in theINFANTMET Cohort. Microbiome. 2017;5:4. doi:10.1186/s40168-016-0213-y.* Correspondence: Catherine.stanton@teagasc.ie2APC Microbiome Institute, University College Cork, Cork, Ireland3Teagasc Moorepark Food Research Centre, Fermoy, Co., Cork, Ireland© The Author(s). 2017 Open Access This articInternational License (http://creativecommonsreproduction in any medium, provided you gthe Creative Commons license, and indicate if(http://creativecommons.org/publicdomain/zele is distributed under the terms of the Creative Commons Attribution 4.0.org/licenses/by/4.0/), which permits unrestricted use, distribution, andive appropriate credit to the original author(s) and the source, provide a link tochanges were made. The Creative Commons Public Domain Dedication waiverro/1.0/) applies to the data made available in this article, unless otherwise stated.

Erratum to: Evolution of gut microbiota composition from birth to 24 weeks in the INFANTMET Cohort

erratumErratum


Following publication of this article [1], it has come to our attention that the name of the author Kieran Tuohy’s name was captured incorrectly as “Touhy” and instead should be Kieran Tuohy

Hill et al. Microbiome  (2017) 5:21 DOI 10.1186/s40168-017-0240-3ERRATUM Open AccessErratum to: Evolution of gut microbiotacomposition from birth to 24 weeks in theINFANTMET CohortCian J. Hill1,2, Denise B. Lynch1,2, Kiera Murphy1,2,3, Marynka Ulaszewska5, Ian B. Jeffery1, Carol Anne O’Shea4,Claire Watkins3, Eugene Dempsey4, Fulvio Mattivi5, Kieran Tuohy5, R. Paul Ross1,2, C. Anthony Ryan2,4,Paul W. O’Toole1,2 and Catherine Stanton2,3*ErratumFollowing publication of this article [1], it has come toour attention that the name of the author KieranTuohy’s name was captured incorrectly as “Touhy” andinstead should be Kieran Tuohy.Author details1School of Microbiology, University College Cork, Cork, Ireland. 2APCMicrobiome Institute, University College Cork, Cork, Ireland. 3TeagascMoorepark Food Research Centre, Fermoy, Co., Cork, Ireland. 4Department ofNeonatology, Cork University Maternity Hospital, Cork, Ireland. 5Food Qualityand Nutrition Department, Research and Innovation Centre, FondazioneEdmund Mach, San Michele All′adige, Italy.Received: 31 January 2017 Accepted: 31 January 2017Reference1. Hill JC, Lynch BD, Murphy K, Ulaszewska M, Jeffery BI, O’Shea CA, Watkins C,Dempsey E, Mattivi F, Tuohy K, Ross PR, Ryan CA, O’ Toole WP, Stanton C.Evolution of gut microbiota composition from birth to 24 weeks in theINFANTMET Cohort. Microbiome. 2017;5:4. doi:10.1186/s40168-016-0213-y.* Correspondence: Catherine.stanton@teagasc.ie2APC Microbiome Institute, University College Cork, Cork, Ireland3Teagasc Moorepark Food Research Centre, Fermoy, Co., Cork, Ireland© The Author(s). 2017 Open Access This articInternational License (http://creativecommonsreproduction in any medium, provided you gthe Creative Commons license, and indicate if(http://creativecommons.org/publicdomain/zele is distributed under the terms of the Creative Commons Attribution 4.0.org/licenses/by/4.0/), which permits unrestricted use, distribution, andive appropriate credit to the original author(s) and the source, provide a link tochanges were made. The Creative Commons Public Domain Dedication waiverro/1.0/) applies to the data made available in this article, unless otherwise stated.

Metadata collected from the Infantmet cohort. Blank space in the metadata table indicates that information on that particular factor was not received for that infant (or mother). Table S2. Preterm infant details and clinical metadata, including gestational age and antibiotic exposure(s). Table S3. Complete list of all oligonucleotides used for PCR amplification. Table S4. The influence of birth mode and getational age on the infant gut microbiota from week 1 to 24 of life. Results of pairwise PerMANOVA tests on Spearman distance matrix between birth modes at given time points, after adjustment for batch effects. p value adjustment was performed using Benjamini-Hochberg. Table S5. Reporting classes of metabolites annotated in urine. Table S6. 2S MS2 and MS3 spectra of annotated biomarkers. Detailed breakdown of the classification of the biomarkers used for metabolomics analysis. Table S7. Prolonged breastfeeding influences FT-CS but not FT-SVD infants’ gut microbiota. PerMANOVA p value results comparing the microbiota of infants breastfed for different durations, after adjusting for potential batch effect. Where birth modes were combined, p values were obtained after adjusting for birth modes. Table S8. Genera found to be significantly different at week 24 between infants that were breastfed for less than, or greater than 4 months. In red (positive log2 fold change) indicates genera that are higher in infants that were breastfed for longer, whereas in green are genera that are lower in infants that were breastfed for longer. Table S9. Pairwise comparisons of Spearman distances between groups of infants at due dates, grouped by the number of weeks early that they were born. PerMANOVA was used on Spearman distance matrix between all samples of the group pairs being tested, and multiple testing. Table S10. Genera found to be differentially abundant, or trending toward significance, between birth modes at week 1. L2FC: Log2 fold change; p.adj: adjusted p value; sig.: significance level. Positive L2FC (in blue) indicates that the genus is higher in the first birth mode of the pair listed, whereas a negative p value (in orange) indicates that the genus is lower in the first birth mode listed. Table S11. Genera found to be differentially abundant, or trending toward significance, between birth modes at week 4. L2FC: Log2 fold change; p.adj: adjusted p value; sig.: significance level. Positive L2FC (in blue) indicates that the genus is higher in the first birth mode of the pair listed, whereas a negative p value (in orange) indicates that the genus is lower in the first birth mode listed. Table S12. Genera found to be differentially abundant, or trending toward significance, between birth modes at week 8. L2FC: Log2 fold change; p.adj: adjusted p value; sig.: significance level. Positive L2FC (in blue) indicates that the genus is higher in the first birth mode of the pair listed, whereas a negative p value (in orange) indicates that the genus is lower in the first birth mode listed. Table S13. Genera found to be differentially abundant, or trending toward significance, between birth modes at week 24. L2FC: Log2 fold change; p.adj: adjusted p value; sig.: significance level. Positive L2FC (in blue) indicates that the genus is higher in the first birth mode of the pair listed, whereas a negative p value (in orange) indicates that the genus is lower in the first birth mode listed. Table S14. Genera found to be differentially abundant, or trending toward significance, between time points for FT-CS. L2FC: Log2 fold change; p.adj: adjusted p value; sig.: significance level. Positive L2FC (in blue) indicates that the genus is higher at the earlier of the two compared time points, whereas a negative p value (in orange) indicates that the genus is lower in the first of the two time points. Table S15. Genera found to be differentially abundant, or trending toward significance, between time points for PT-CS. L2FC: Log2 fold change; p.adj: adjusted p value; sig.: significance level. Positive L2FC (in blue) indicates that the genus is higher at the earlier of the two compared time points, whereas a negative p value (in orange) indicates that the genus is lower in the first of the two time points. Table S16. Genera found to be differentially abundant, or trending toward significance, between time points for FT-SVD. L2FC: Log2 fold change; p.adj: adjusted p value; sig.: significance level. Positive L2FC (in blue) indicates that the genus is higher at the earlier of the two compared time points, whereas a negative p value (in orange) indicates that the genus is lower in the first of the two time points. Table S17. Genera found to be significantly different, or trending toward different, between time points for PT-SVD. L2FC: Log2 fold change; p.adj: adjusted p value; sig.: significance level. Positive L2FC (in blue) indicates that the genus is higher at the earlier of the two compared time points, whereas a negative p value (in orange) indicates that the genus is lower in the first of the two time points. Table S18. Significant negative correlations of abundances of genera pairs. Correlations were tested with Pearson correlation. The false discovery rate was adjusted for with Benjamini-Hochberg adjustment. (XLSX 188 kb

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Additional file 1: Table S1. of Evolution of gut microbiota composition from birth to 24 weeks in the INFANTMET Cohort

Background
                The gut is the most extensively studied niche of the human microbiome. The aim of this study was to characterise the initial gut microbiota development of a cohort of breastfed infants (n = 192﻿) from 1 to 24 weeks of age.
              
              
                Methods
                V4-V5 region 16S rRNA amplicon Illumina sequencing and, in parallel, bacteriological culture. The metabolomic profile of infant urine at 4 weeks of age was also examined by LC-MS.
              
              
                Results
                Full-term (FT), spontaneous vaginally delivered (SVD) infants’ microbiota remained stable at both phylum and genus levels during the 24-week period examined. FT Caesarean section (CS) infants displayed an increased faecal abundance of Firmicutes (p < 0.01) and lower abundance of Actinobacteria (p < 0.001) after the first week of life compared to FT-SVD infants. FT-CS infants gradually progressed to harbouring a microbiota closely resembling FT-SVD (which remained stable) by week 8 of life, which was maintained at week 24. The gut microbiota of preterm (PT) infants displayed a significantly greater abundance of Proteobacteria compared to FT infants (p < 0.001) at week 1.
                Metabolomic analysis of urine at week 4 indicated PT-CS infants have a functionally different metabolite profile than FT (both CS and SVD) infants. Co-inertia analysis showed co-variation between the urine metabolome and the faecal microbiota of the infants. Tryptophan and tyrosine metabolic pathways, as well as fatty acid and bile acid metabolism, were found to be affected by delivery mode and gestational age.
              
              
                Conclusions
                These findings confirm that mode of delivery and gestational age both have significant effects on early neonatal microbiota composition. There is also a significant difference between the metabolite profile of FT and PT infants. Prolonged breastfeeding was shown to have a significant effect on the microbiota composition of FT-CS infants at 24 weeks of age, but interestingly not on that of FT-SVD infants. Twins had more similar microbiota to one another than between two random infants, reflecting the influence of similarities in both host genetics and the environment on the microbiota.﻿This work was supported by the Government of Ireland National Development Plan by way of a Department of Agriculture, Food and Marine FIRM grant to the INFANTMET project (CS), by a grant from the Health Research Board of Ireland (HRA_POR/2012/123) to PWOT, by the APC Microbiome Institute, and by the BIO-IT Platform

O\u27Shea, Carol A

O\u27Toole, Paul W.

Irish Universities

Evolution of gut microbiota composition from birth to 24 weeks in the INFANTMET Cohort

Cian J. Hill

Denise B. Lynch

Kiera Murphy

Marynka Ulaszewska

Ian B. Jeffery

Carol Anne O’Shea

Claire Watkins

Eugene Dempsey

Fulvio Mattivi

Kieran Tuohy

R. Paul Ross

C. Anthony Ryan

Paul W. O’ Toole

Catherine Stanton

Crossref

Erratum: Following publication of this article, it has come to our attention that the name of the author Kieran Tuohy’s name was captured incorrectly as “Touhy” and instead should be Kieran Tuohy

Hill, Cian J.

Lynch, Denise B.

Jeffery, Ian B.

O'Shea, Carol Anne

Dempsey, Eugene M.

Ross, R. Paul

Stanton, Catherine

Cork Open Research Archive

Title Erratum to: Evolution of gut microbiota composition from birth to 24weeks in the INFANTMET CohortAuthor(s) Hill, Cian J.; Lynch, Denise B.; Murphy, Kiera; Ulaszewska, Marynka;Jeffery, Ian B.; O'Shea, Carol Anne; Watkins, Claire; Dempsey, EugeneM.; Mattivi, Fulvio; Tuohy, Kieran; Ross, R. Paul; Ryan, C. Anthony;O'Toole, Paul W.; Stanton, CatherinePublication date 2017-02-14Original citation Hill, C. J., Lynch, D. B., Murphy, K., Ulaszewska, M., Jeffery, I. B.,O’Shea, C. A., Watkins, C., Dempsey, E., Mattivi, F., Tuohy, K., Ross,R. P., Ryan, C. A., O’Toole, P. W. and Stanton, C. (2017) ‘Erratum to:Evolution of gut microbiota composition from birth to 24 weeks in theINFANTMET Cohort’, Microbiome, 5 (21).  doi:10.1186/s40168-017-0240-3Type of publication OtherLink to publisher'sversionuri:http://dx.doi.org/10.1186/s40168-016-0213-yhttp://dx.doi.org/10.1186/s40168-017-0240-3Access to the full text of the published version may require asubscription.Rights © 2017, the Authors. Open Access. This article is distributed underthe terms of the Creative Commons Attribution 4.0 InternationalLicense (http://creativecommons.org/licenses/by/4.0/), which permitsunrestricted use, distribution, and reproduction in any medium,provided you give appropriate credit to the original author(s) andthe source, provide a link to the Creative Commons license, andindicate if changes were made. The Creative Commons PublicDomain Dedication waiver(http://creativecommons.org/publicdomain/zero/1.0/) applies to thedata made available in this article, unless otherwise stated.http://creativecommons.org/licenses/by/4.0/Item downloadedfromhttp://hdl.handle.net/10468/3704Downloaded on 2017-09-04T23:36:02ZERRATUM Open AccessErratum to: Evolution of gut microbiotacomposition from birth to 24 weeks in theINFANTMET CohortCian J. Hill1,2, Denise B. Lynch1,2, Kiera Murphy1,2,3, Marynka Ulaszewska5, Ian B. Jeffery1, Carol Anne O’Shea4,Claire Watkins3, Eugene Dempsey4, Fulvio Mattivi5, Kieran Tuohy5, R. Paul Ross1,2, C. Anthony Ryan2,4,Paul W. O’Toole1,2 and Catherine Stanton2,3*ErratumFollowing publication of this article [1], it has come toour attention that the name of the author KieranTuohy’s name was captured incorrectly as “Touhy” andinstead should be Kieran Tuohy.Author details1School of Microbiology, University College Cork, Cork, Ireland. 2APCMicrobiome Institute, University College Cork, Cork, Ireland. 3TeagascMoorepark Food Research Centre, Fermoy, Co., Cork, Ireland. 4Department ofNeonatology, Cork University Maternity Hospital, Cork, Ireland. 5Food Qualityand Nutrition Department, Research and Innovation Centre, FondazioneEdmund Mach, San Michele All′adige, Italy.Received: 31 January 2017 Accepted: 31 January 2017Reference1. Hill JC, Lynch BD, Murphy K, Ulaszewska M, Jeffery BI, O’Shea CA, Watkins C,Dempsey E, Mattivi F, Tuohy K, Ross PR, Ryan CA, O’ Toole WP, Stanton C.Evolution of gut microbiota composition from birth to 24 weeks in theINFANTMET Cohort. Microbiome. 2017;5:4. doi:10.1186/s40168-016-0213-y.* Correspondence: Catherine.stanton@teagasc.ie2APC Microbiome Institute, University College Cork, Cork, Ireland3Teagasc Moorepark Food Research Centre, Fermoy, Co., Cork, Ireland© The Author(s). 2017 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, andreproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link tothe Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.Hill et al. Microbiome  (2017) 5:21 DOI 10.1186/s40168-017-0240-3

Erratum to: Evolution of gut microbiota composition from birth to 24 weeks in the INFANTMET Cohort

Paul W. O’Toole

Springer - Publisher Connector

Hill et al. Microbiome  (2017) 5:21 
DOI 10.1186/s40168-017-0240-3ERRATUM Open AccessErratum to: Evolution of gut microbiota
composition from birth to 24 weeks in the
INFANTMET Cohort
Cian J. Hill1,2, Denise B. Lynch1,2, Kiera Murphy1,2,3, Marynka Ulaszewska5, Ian B. Jeffery1, Carol Anne O’Shea4,
Claire Watkins3, Eugene Dempsey4, Fulvio Mattivi5, Kieran Tuohy5, R. Paul Ross1,2, C. Anthony Ryan2,4,
Paul W. O’Toole1,2 and Catherine Stanton2,3*Erratum
Following publication of this article [1], it has come to
our attention that the name of the author Kieran
Tuohy’s name was captured incorrectly as “Touhy” and
instead should be Kieran Tuohy.
Author details
1School of Microbiology, University College Cork, Cork, Ireland. 2APC
Microbiome Institute, University College Cork, Cork, Ireland. 3Teagasc
Moorepark Food Research Centre, Fermoy, Co., Cork, Ireland. 4Department of
Neonatology, Cork University Maternity Hospital, Cork, Ireland. 5Food Quality
and Nutrition Department, Research and Innovation Centre, Fondazione
Edmund Mach, San Michele All′adige, Italy.
Received: 31 January 2017 Accepted: 31 January 2017
Reference
1. Hill JC, Lynch BD, Murphy K, Ulaszewska M, Jeffery BI, O’Shea CA, Watkins C,
Dempsey E, Mattivi F, Tuohy K, Ross PR, Ryan CA, O’ Toole WP, Stanton C.
Evolution of gut microbiota composition from birth to 24 weeks in the
INFANTMET Cohort. Microbiome. 2017;5:4. doi:10.1186/s40168-016-0213-y.* Correspondence: Catherine.stanton@teagasc.ie
2APC Microbiome Institute, University College Cork, Cork, Ireland
3Teagasc Moorepark Food Research Centre, Fermoy, Co., Cork, Ireland
© The Author(s). 2017 Open Access This artic
International License (http://creativecommons
reproduction in any medium, provided you g
the Creative Commons license, and indicate if
(http://creativecommons.org/publicdomain/zele is distributed under the terms of the Creative Commons Attribution 4.0
.org/licenses/by/4.0/), which permits unrestricted use, distribution, and
ive appropriate credit to the original author(s) and the source, provide a link to
changes were made. The Creative Commons Public Domain Dedication waiver
ro/1.0/) applies to the data made available in this article, unless otherwise stated.


O\u27Shea, Carol Anne