The 10th International Symposium on Poisonous Plants (ISOPP) was held on September 16-20, 2018 at the Red Lion Conference Center in St. George, Utah, USA. The meeting was truly international with 55 attendees from across the globe. The attendees were a diverse mix of research scientists, academicians, students, veterinarians, private industry representatives, extension agents and government regulators. Dr. Joseph Betz, Acting Director of the Office of Dietary Supplements at the National Institutes of Health, was the plenary speaker for the symposium, wherein he spoke regarding the safety of botanical supplements. There were six sessions of oral presentations including sessions on Global Perspectives on Poisonous Plants, Natural Toxins and the Systems They Affect, Emerging Poisonous Plant Problems, Diagnostics, and Advances in Research. Two posters sessions provided a great opportunity for interaction and discussion. The highlight of the meeting was an evening banquet whereupon Drs. Anthony Knight, Kip Panter, Steven Colegate, and Franklin Riet-Correa were honored with the ISOPP Lifetime Achievement Award. These four individuals dedicated their scientific careers to studying poisonous plants. They were also key players in many of the previous ISOPPs. There was also time for networking and socializing during a bus tour of Southern Utah / Northern Arizona to observe the natural plant communities in these areas as well as during a Dutch oven dessert social one evening. We are already looking forward to the next ISOPP, which is going to be held at the veterinary school campus in Lyon, France in July of 2021 or 2022. Stay tuned for further developments. We hope to see you all there