Integrity Testing of Gas Permeable Silicone Filters

Abstract

This report investigates the most reasonable, cost efficient, and reliable ways to integrity test a filter made from a permeable silicone membrane for future biomedical and pharmaceutical applications. The goal of the project was to create a fixture that a pharmaceutical company can use to quickly and reliably test the integrity of the filter. A variety of methods are outlined to test the integrity of the filter, after a series of quantitative tests, a single method was established that meet the requirements most thoroughly. The method that was determined to be most effective involves a series of components including a flow meter and pressure regulator to demonstrate the Flow Meter Test . Following a strict schedule and close communication and mentoring from Dr. Lazzara, a reliable way for medical professionals to test the integrity of the filters was determined and is outlined in this report

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