A high sensitivity and low power circuit for the measurement of abnormal blood cell levels

Abstract

This paper describes a technique to detect blood cell levels based on the time-period modulation of a relaxation oscillator loaded with an Inter Digitated Capacitor (IDC). A digital readout circuit has been proposed to measure the time-period difference between the two oscillators loaded with samples of healthy and (potentially) unhealthy blood. A prototype circuit was designed in 65nm CMOS technology and post-layout simulations shows 15.25aF sensitivity. The total circuit occupies 2184µm2 silicon area and consumes 216µA from a 1V power supply

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