The aim of the systematic review is to critically appraise, synthesise and present the available evidence of patients' lived experiences of cytotoxic medications prescribed for the management of malignant solid tumours. In relation to the patients pharmacological treatment journey for the management of malignant solid tumours: What are the patients' lived experience? What is the medication related burden? What are the medication related beliefs? What is the medication taking practice? What is the relationship between the lived experience and medication related burden, medication related beliefs and medication taking practice

Bonanno, Patricia Vella

Brincat, Alison

Stewart, Derek

Weidmann, Anita

English

The aim of the systematic review is to critically appraise, synthesise and present the available evidence of patients’ lived experiences of cytotoxic medications prescribed for the management of malignant solid tumours. In relation to the patients’ pharmacological treatment journey for the management of malignant solid tumours: • What are the patients’ lived experience? • What is the medication related burden? • What are the medication related beliefs? • What is the medication taking practice? • What is the relationship between the lived experience and medication related burden, medication related beliefs and medication taking practice?peer-reviewe

Vella Bonanno, Patricia

OAR@UM

Patients’ lived experiences of cytotoxic medications prescribed for the management of malignant solid tumours : a systematic review

Open Access Institutional Repository at Robert Gordon University

   AUTHOR(S):   TITLE:    YEAR:   Original citation:    OpenAIR citation:   Version history:    Copyright statement:    OpenAIR takedown statement: This systematic review protocol forms part of research that has been funded by _____________________________. The protocol document was originally hosted by _______________________________________ and made publicly available at ____________________________________________________________________________________. This  work  is  made  freely available  under  open access. The first version of this protocol was originally made available on ________________________________________. This version of the protocol was originally made available on ____________________________________________. In total, there have been ____________ known revisions of the protocol.       This protocol is distributed under a CC ____________ license._________________________________________________________________________  Section 6 of  the “Repository policy  for OpenAIR @ RGU”  (available  from http://www.rgu.ac.uk/staff‐and‐current‐students/library/library‐policies/repository‐policies)  provides  guidance  on  the  criteria  under  which  RGU  will consider withdrawing material from OpenAIR. If you believe that this item is subject to any of these criteria, or for any other reason should not be held on OpenAIR, then please contact openair‐help@rgu.ac.uk with the details of the item and the nature of your complaint.  PROSPEROInternational prospective register of systematic reviews Patients’ lived experiences of cytotoxic medications prescribed for the management ofmalignant solid tumours: a systematic review Alison Brincat, Lorna Marie West, Derek Stewart, Anita Weidmann Citation Alison Brincat, Lorna Marie West, Derek Stewart, Anita Weidmann. Patients’ lived experiences ofcytotoxic medications prescribed for the management of malignant solid tumours: a systematicreview. PROSPERO 2016 CRD42016048457 Available from: http://www.crd.york.ac.uk/PROSPERO/display_record.php?ID=CRD42016048457 Review questionThe aim of the systematic review is to critically appraise, synthesise and present the available evidence ofpatients’ lived experiences of cytotoxic medications prescribed for the management of malignant solidtumours. In relation to the patients’ pharmacological treatment journey for the management of malignant solidtumours:• What are the patients’ lived experience?• What is the medication related burden? • What are themedication related beliefs?• What is the medication taking practice?• What is the relationship between thelived experience and medication related burden, medication related beliefs and medication taking practice? SearchesSystematic review according to PRISMA guidelines will be conducted in the following databases: CINAHL,MEDLINE, Cochrane Library, Science Direct, Springerlink, International pharmaceutical abstracts andPsycArticles. Manual searches of related studies listed in the reference, footnote and citations will be carried out to includemore relevant papers. The search will be restricted to publications in the English language and will centre onthe concepts of patients’ lived experience, cytotoxic medications and malignant solid tumours. Conceptmapping was applied to develop keywords and generate search terms. Types of study to be includedAll study designs of research studies which have employed any methodological approach includingquantitative or mixed methodologies will be included. Condition or domain being studiedThe lived experiences of adult patients prescribed cytotoxic medications for the management of malignantsolid tumours. Participants/populationInclusion criteria: patients who are 18 years and over irrespective of their gender, ethnicity and stage ofdisease receiving cytotoxic medications for the management of malignant solid tumours. Intervention(s), exposure(s)Articles will be reviewed if they describe the patients’ lived experience of cytotoxic medications for themanagement of malignant solid tumours. Comparator(s)/controlNot applicable. Context Primary outcome(s)The primary outcomes will include the experiences, burden, beliefs and practice of patients in relation to                               Page: 1 / 3 PROSPEROInternational prospective register of systematic reviewscytotoxic medications. Secondary outcome(s)None. Data extraction (selection and coding)The initial screening of all titles retrieved during the search will be carried out to identify potentially relevantpapers. This will be followed by screening of abstracts and then by full paper against the pre-definedsystematic review aim, questions and inclusion/exclusion criteria. A random sample of 10% of the retrievedtitles and abstracts during the search strategy will be independently checked by two research members forconsistency of inclusion/exclusion and enhance the reliability of the process. Any disagreement will beresolved by consensus within the research team; otherwise these will be reported in the final review. Anyduplicate publications of the same studies will be eliminated and the number of duplicates will be recordedusing Prisma 2009 flow diagram.Qualitative and quantitative data extraction will be conducted using standardised data extraction tools. Thesewill be developed so as to obtain specific information pertinent to the review aim and questions. Risk of bias (quality) assessmentQuality assessment will be conducted on all included manuscripts by two independent reviewers usingestablished critical appraisal tools. Disagreements will be resolved by consensus after discussion with theresearch team. Strategy for data synthesisDepending on the uncertainty of data that will be retrieved, it is difficult to anticipate strategies for datasynthesis. However the synthesis would most likely be narrative. Key findings and conclusion will begenerated in relation to the review aim and questions. Analysis of subgroups or subsetsNone planned Contact details for further informationMs Brincata.brincat@rgu.ac.uk Organisational affiliation of the reviewRobert Gordon University, Aberdeen Scotland Review team members and their organisational affiliationsMs Alison Brincat. School of Pharmacy and Life Sciences, Robert Gordon University, Aberdeen ScotlandDr Lorna Marie West. School of Pharmacy and Life Sciences, Robert Gordon University, Aberdeen Scotlandand Department of Clinical Pharmacology and Therapeutics, University of Malta, Msida MaltaProfessor Derek Stewart. School of Pharmacy and Life Sciences, Robert Gordon University, AberdeenScotlandDr Anita Weidmann. School of Pharmacy and Life Sciences, Robert Gordon University, Aberdeen Scotland Anticipated or actual start date01 October 2016 Anticipated completion date28 February 2017 Funding sources/sponsorsThe project will be funded by the ‘Get Qualified Scheme’ upon successful completion of the doctoratecourse.                               Page: 2 / 3 PROSPEROInternational prospective register of systematic reviews Conflicts of interestNone known LanguageEnglish CountryScotland Stage of reviewReview_Ongoing Subject index terms statusSubject indexing assigned by CRD Subject index termsAntineoplastic Agents; Disease Management; Humans; Neoplasms Date of registration in PROSPERO27 September 2016 Date of publication of this version27 September 2016 Details of any existing review of the same topic by the same authors Stage of review at time of this submissionThe review has not started Stage Started CompletedPreliminary searches No NoPiloting of the study selection process No NoFormal screening of search results against eligibility criteria No NoData extraction No NoRisk of bias (quality) assessment No NoData analysis No No Versions 27 September 2016PROSPEROThis information has been provided by the named contact for this review. CRD has accepted this information in goodfaith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registrationrecord, any associated files or external websites. Powered by TCPDF (www.tcpdf.org)                               Page: 3 / 3

Patients' lived experiences of cytotoxic medications prescribed for the management of malignant solid tumours: a systematic review. [Protocol]

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Patients' lived experiences of cytotoxic medications prescribed for the management of malignant solid tumours: a systematic review.

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