Architecture bridges between art and science, calling for a harmonious balance of multiple needs and complex issues. Considering that architecture is a man’s creation for men, this research explores it from the relationship of human factors in architecture. It specifically focuses on the relationships between users and natural light (both sunlight and daylight) in the architectural production of the 20th century. A critical review is undertaken for the case of the 20th century most famous modern architects in terms of architectural daylighting and its relationships to the users' perception and behaviour. The investigative approach relies on a literature review, in situ observations and some interviews with the current buildings’ managers. Six contemporary architects’ work composed the study corpus. The results highlight first that i) users did not perceive natural light as architects did, ii) users’ feelings could not replace the other factors contributing to the generation of the comfort satisfaction, and iii) after the disappearance of the sensation effect, a dissatisfaction one occurred and often generates transformations disfiguring the striking effects initially designed by the architects