Acknowledgements We would like to acknowledge NHS Grampian Endowment funds and TENOVUS Scotland for funding. JL was funded by a scholarship from Fraserburgh Moonlight Prowl and AAS was funded by the Scottish Government’s Rural and Environment Science and Analytical Services Division (RESAS). We also thank Dr Raphael Mechoulam, University of Jerusalem, for the gift of the endocannabinoids.Peer reviewedPostprin