This work is supported by the National Natural Science Foundation of China (Grant Nos. 81320108025, 61402194, 61572227), Development Project of Jilin Province of China (20140101180JC) and China Postdoctoral Science Foundation (2014T70291).Postprin

Chen, Xin

Du, Wei

Liang, Yanchun

Pang, Wei

Wang, Yan

Xu, Ying

Zhang, Chi

English

A computational pipeline is developed to accurately predict urine excretoryproteins and the possible origins of the proteins. The novel contributionsof this study include: (i) a new method for predicting if a cellular protein isurine excretory based on unique features of proteins known to be urine excretory; and (ii) a novel method for identifying urinary proteins originating from the urinary system. By integrating these tools, our computational pipeline is capable of predicting the origin of a detected urinary protein, hence offering a novel tool for predicting potential biomarkers of a specific disease, which may have some of their proteins urine excreted. One application is presented for this prediction pipeline to demonstrate the effectiveness of its prediction. The pipeline and supplementary materials can be accessed at the following URL:http://csbl.bmb.uga.edu/PUEPro

Heriot Watt Pure

PUEPro:A Computational Pipeline for Prediction of Urine Excretory Proteins

Yan Wang

Wei Du

Yanchun Liang

Xin Chen

Chi Zhang

Wei Pang

Ying Xu

Crossref

PUEPro: A Computational Pipeline for Prediction of Urine Excretory Proteins

This work is supported by the National Natural Science Foundation of China (Grant Nos. 81320108025, 61402194, 61572227), Development Project of Jilin Province of China (20140101180JC) and China Postdoctoral Science Foundation (2014T70291)

Aberdeen University Research

PUEPro : A Computational Pipeline for Prediction of Urine Excretory Proteins

https://aura.abdn.ac.uk/bitstream/2164/9596/1/PUEPro20160928wy_WP0929_1_.pdf

PUEPro : A Computational Pipeline for Prediction of Urine Excretory Proteins

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Heriot Watt Pure

Crossref

Aberdeen University Research

Heriot Watt Pure