Funding: This research project was funded in part by the Strategic Research Excellence Initiative 2020 (SREI2020), University of Sydney to JE and the University of Sydney HMR + Implementation Funding Grant to VC, DLC and SS.Peer reviewedPublisher PD

Cogger, Victoria C.

Eberhard, Joerg

Le Couteur, David G.

Morimoto, J.

Pulpitel, Tamara

Raubenheimer, D.

Ruiz, Kate

Senior, Alistair

Simpson, Stephen J

Solon-Biet, Samantha M.

Wali, Jibran A

PLoS ONE

English

Funding: This research project was funded in part by the Strategic Research Excellence Initiative 2020 (SREI2020), University of Sydney to JE and the University of Sydney HMR + Implementation Funding Grant to VC, DLC and SS.Peer reviewe

Aberdeen University Research

Sucrose and starch intake contribute to reduced alveolar bone height in a rodent model of naturally occurring periodontitis

While there is a burgeoning interest in the effects of nutrition on systemic inflammatory diseases, how dietary macronutrient balance impacts local chronic inflammatory diseases in the mouth has been largely overlooked. Here, we used the Geometric Framework for Nutrition to test how the amounts of dietary macronutrients and their interactions, as well as carbohydrate type (starch vs sucrose vs resistant starch) influenced periodontitis-associated alveolar bone height in mice. Increasing intake of carbohydrates reduced alveolar bone height, while dietary protein had no effect. Whether carbohydrate came from sugar or starch did not influence the extent of alveolar bone height. In summary, the amount of carbohydrate in the diet modulated periodontitis-associated alveolar bone height independent of the source of carbohydrates

Juliano Morimoto

Alistair Senior

Kate Ruiz

Jibran A Wali

Tamara Pulpitel

Samantha M Solon-Biet

Victoria C Cogger

David Raubenheimer

David G Le Couteur

Stephen J Simpson

Joerg Eberhard

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Sucrose and starch intake contribute to reduced alveolar bone height in a rodent model of naturally occurring periodontitis.

https://aura.abdn.ac.uk/bitstream/2164/13811/1/Morimoto_etal_pone_Sucrose_and_starch_VOR.pdf

Sucrose and starch intake contribute to reduced alveolar bone height in a rodent model of naturally occurring periodontitis

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Aberdeen University Research

Directory of Open Access Journals