We develop a operator algebraic model for twisted K-theory, which includes
the most general twistings as a generalized cohomology theory (i.e. all those
classified by the unit spectrum bgl1(KU)). Our model is based on strongly
self-absorbing C∗-algebras. We compare it with the known homotopy theoretic
descriptions in the literature, which either use parametrized stable homotopy
theory or ∞-categories. We derive a similar comparison of analytic
twisted K-homology with its topological counterpart based on generalized Thom
spectra. Our model also works for twisted versions of localizations of the
K-theory spectrum, like KU[1/n] or KUQ.Comment: 28 page